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Which type of cyst can contain keratinizing material and can be either unilocular or multi-locular?

Dentigerous cyst

Odontogenic keratocyst

The odontogenic keratocyst is characterized by its potential to contain keratinized material and the ability to present as either unilocular or multilocular. This cyst originates from the dental lamina and is notable for its aggressive behavior and high recurrence rate.

What distinguishes the odontogenic keratocyst from other types is the presence of a lining that can exhibit keratinization, which is a key feature in its histology. The cyst may develop as a single chamber (unilocular) or as multiple interconnected chambers (multilocular), reflecting its various presentations in clinical scenarios. Its unique attributes make it an important subject of study in dental pathology.

In contrast, other types of cysts listed, such as the dentigerous cyst, typically present around the crown of an unerupted tooth and do not have the same tendency for keratinization. The globulomaxillary cyst and nasopalatine duct cyst also lack the characteristic multilocular presentation and keratinized content seen in odontogenic keratocysts. These distinctions highlight why the odontogenic keratocyst fits the description provided in the question.

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Globulomaxillary cyst

Nasopalatine duct cyst

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